96% up by HPLC, USP, GMP Atracurium Besylate 64228-81-5

Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:96% up by HPLC, USP, GMP Atracurium Besylate 64228-81-5
CAS No.:64228-81-5
Standard:USP, BP, EP, JP, In-house Standards
Price(USD):Negotiable
Company:Sinoway Industrial Co.Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Xiamen, Fujian

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

  • Monthly Production Capacity: 1000kg

    Packaging Information: 25kg/drum 1kg/bottle

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/L

    Product Information

     

    Product name

    Atracurium Besylate

    CAS No.

    64228-81-5

    Molecular Formula

    C53H72N2O12.2(C6H5O3S)

    Molecular Weight

    257.60

    Quality Standard

    96% up by HPLC, GMP,USP

    Appearance

    White or almost white powder

     

    COA of Atracurium Besylate

     

    ITEMS

    SPECIFICATION

    RESULT

    Appearance:

    white or almost white powder,

    slightly hygroscopic, ordorless

     

     Confirms

    Very solutable in acetonitrile or chloroform, Soluble in Water, very soluble and practically insolutable in ethyl ether

     Confirms

    Identification

    (1) IR

    Conforms

     (2) HPLC

    Conforms

    Water

    ≤ 5.0%

    0.6%

    Residue on ignition

    ≤ 0.2%

    0.1%

    Methyl benzenesulfonate

    ≤ 0.1%

    Undetected

    Toluene

    ≤ 890ppm (ICH)

    102ppm

    Chromatographic purity

    (1) Laudanosine: ≤ 0.5%

    (2) Other individual impurities: ≤ 1.0%

    (3) Total Impurities: ≤ 3.5%

    0.01%

    0.38%

    1.3%

    Isomer Ratio

    Trans-Trans Isomer: 5%-6.5%

    5.7%

     

    Cis-Trans Isomer: 34.5%-38.5%

    36%

     

    Cis-Cis Isomer: 55%-60%

    58.2%

    Assay

    96%-102%

      (C65H82N2O18S2 on anhydrous basis)

    100.2%

    Residue Solvents

    (1) Dichloromethane: ≤ 600ppm

    (2) Acctonitrile: ≤ 410ppm

    (3) Ethyl ether: ≤ 5000ppm

    Undetected

    Undetected

    1739ppm

    Result

    Confirms to USP34

     

    Usage

     

    Function of Atracurium Besylate

    Atracurium besylate is a skeletal muscle relaxant for general anesthesia, suitable for the treatment of muscle relaxation for endotracheal intubation and for muscle relaxation required for thoracic and abdominal surgery. Like most neuromuscular blocking agents, it can Causes the release of histamine, skin flushing, transient hypotension, and occasionally bronchospasm. Caution should be used in patients with myasthenia gravis, neuromuscular disease, and severe electrolyte disturbances, as it potentiates the effects of other non-depolarizing agents. People with severe cardiovascular disease are more sensitive to the transient hypotensive reaction of this product, so it is recommended to give slow intravenous injection in divided doses.

     

Send your message to this supplier
  • From:
  • To:
    Sinoway Industrial Co.Ltd.
  • Send a Copy to this Email
  • Message:
    Upload Images / Files
    - Supports jpg, jpeg, png,
     gif, pdf, doc, docx,
     xls, xlsx, txt, rar and zip
    - Max upload 3 files;
     Max  total size: 3MB
    (0/3)

    Enter between 20 to 4,000 characters.This is not what you are looking for ? Post a Sourcing Request Now

  • Verification:
PharmaSources Customer Service