98% up by HPLC DMF Eptifibatide Acetate 148031-34-9

Category:Bio Products > Protein/Antigen/Polypeptide > Other Protein
Product Name:98% up by HPLC DMF Eptifibatide Acetate 148031-34-9
CAS No.:148031-34-9
Standard:In-house Standards
Price(USD):Negotiable
Company:Sinoway Industrial Co.Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Xiamen Fujian

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Monthly Production Capacity: 10ton/year

    Packaging Information: 25kg/drum; 5kg/bag, 1kg/bag

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/L

     

    Product Information

     

    Product name

    Eptifibatide acetate

    Sequence

    Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2

    CAS No.

    188627-80-7 (Eptifibatide (net)),

    148031-34-9 (Eptifibatide acetate)

    Molecular Formula

    C35H49N11O9S2

    Molecular Weight

    832.4

    Molecule Structure

    Quality Standard

    98% up by HPLC, GMP

    Appearance

    White slightly yellwish powder

     

    COA of Eptifibatide Acetate

     

     

    Items

    Specification

    Results

    Appearance

    White slightly yellwish powder

    Conforms

    Purity(HPLC)

    > 98%

    99.57%

    Peptide

    ≥ 80%

     

    Amino acids

    Asp:0.85-1.15

    Cys:0.75-1.15

    Gly:0.85-1.15

    Pro: 0.85-1.15

    Har: 0.85-1.15

    Trp:Present

    1.08

    1.00

    0.98

    1,06

    1.07

    Specific optical rotation

    -53- -57°(C=5, 1% Acetic acid)

    -55.6°

    Solubility

    Soluble in water and 1% acetic acid at a concentration of ≥ 1mg/ml to give a clear, colorless solution

    Conforms

    Related substances (HPLC)

    Total impurities: ≤ 1.5%
    Any impurity: ≤ 1.0%

    0.6%

    0.2%

    Water (Karl Fischer)

    ≤ 5.0 %

    3.8%

    Acetic acid (HPLC)

    ≤ 10.0%

    8.7%

    Bacterial endotoxins

    < 10EU/mg

    Conforms

    Mass balance

    95.0%-105.%

    98.11%

    DMF (GC)

    ≤0.088%

    Conforms

    can

    ≤0.041%

    Conforms

    Conclusion

    Complies with the standard.

     

    Usage

     

    Function of Eptifibatide acetate

    Eptifibatide acetate is a cyclic heptapeptide, a glycoprotein IIb/IIIa receptor inhibitor, and has antiplatelet activity.

     

    Application of Eptifibatide acetate

     

    Eptifibatide acetate is used for the treatment of acute coronary syndrome (unstable angina pectoris/non-ST-elevation myocardial infarction), including patients who will receive medical treatment or who are planning to undergo percutaneous coronary intervention (PCI).

     

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