98% up by HPLC GMP Somatostatin Acetate 38916-34-6

Category:Bio Products > Protein/Antigen/Polypeptide > Other Protein
Product Name:98% up by HPLC GMP Somatostatin Acetate 38916-34-6
CAS No.:38916-34-6
Standard:In-house Standards
Price(USD):Negotiable
Company:Sinoway Industrial Co.Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Xiamen Fujian

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Monthly Production Capacity: 10ton/year

    Packaging Information: 25kg/drum; 5kg/bag, 1kg/bag

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/L

    Product Information

     

    Product name

    Somatostatin acetate

    Alias

    Somatostatina, Somatostatine, Somatostatinum, Somatostatin, cyclic, Somatostatin-14, Aminopan, Panhibin, Somiaton

    CAS No.

    38916-34-6

    Molecular Formula

    C76H104N18O19S2

    Molecular Weight

    1637.87

    Molecule Structure

    Quality Standard

    98% up by HPLC, GMP

    Appearance

    White powder

     

    COA of Somatostatin Acetate

     

    Items

    Specification

    Results

    Appearance

    White Powder

    Conforms

    Purity(HPLC)

    > 98%

    99.57%

    Specific optical rotation (anhydrous and acetic acid-free substance)

    -37° to -47°

    -41°

    Solubility

    freely soluble in water and in acetic acid, practically insoluble in methylene chloride

    Conforms

    Related substances (HPLC)

    Total impurities: NMT 2.0%
    Any impurity: NMT 1.0%

    1.3%

    0.3%

    Water (Karl Fischer)

    NMT 8.0 %

    6.5%

    Acetic acid (HPLC)

    3.0% to 15.0 %

    8.7%

    Bacterial endotoxins

    < 10IU/mg

    Conforms

    Assay (anhydrous and acetic acid-free substance)

    95.0% to 104.0%

    99.34%

    Conclusion

    Complies with the standard.

     

    Usage

     

    Function of Somatostatin Acetate

    Somatostatin Acetate is a peptide hormone that regulates the endocrine system and affects neurotransmission and cell proliferation through its interaction with G protein.

     

    ① It can inhibit the secretion of growth hormone, thyroid stimulating hormone, insulin and glucagon.

    ②It can inhibit the secretion of gastric acid stimulated by the test meal and 5-peptide gastrin, and can inhibit the release of pepsin and gastrin.

    ③It can significantly reduce visceral blood flow, reduce portal vein pressure, reduce blood flow and pressure of collateral circulation, and reduce liver blood flow.

    ④Reduce the secretion of the pancreas and the secretion of the small intestine and gallbladder, reduce enzyme activity, and have a protective effect on pancreatic cells.

    ⑤ It can affect the absorption and nutritional function of the gastrointestinal tract.

     

     

    Application of Somatostatin Acetate

     

    Somatostatin Acetate can be used for severe and acute gastric and duodenal ulcer bleeding; acute erosive or hemorrhagic gastritis severe and acute bleeding; prevention of post-pancreatic complications after pancreatic surgery; inhibition of pancreas and Adjuvant treatment for severe secretion of leaky duct after upper small intestine surgery; regulating human differentiated gastric cancer cell lines

     

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