98% up by HPLC, USP, EP, CEP Oxytocin Acetate 50-56-6

Category:Bio Products > Protein/Antigen/Polypeptide > Other Protein
Product Name:98% up by HPLC, USP, EP, CEP Oxytocin Acetate 50-56-6
CAS No.:50-56-6
Standard:In-house Standards
Price(USD):Negotiable
Company:Sinoway Industrial Co.Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Xiamen Fujian

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa

  • Monthly Production Capacity: 10ton/year

    Packaging Information: 25kg/drum; 5kg/bag, 1kg/bag

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/L

     

    Product Information

     

    Product name

    Oxytocin Acetate

    CAS No.

    50-56-6

    Molecular Formula

    C43H66N12O12S2

    Molecular Weight

    1007.33

    Molecule Structure

    Quality Standard

    98% up by HPLC, USP/EP, CEP

    Appearance

    White powder

     

    COA of Oxytocin Acetate

     

    Items

    Specification

    Results

    Appearance

    White powder

    Conforms

    Solubility

    Soluble in water or 1% acetic acid at a concentration of ≥1mg/ml to give a clear, colorless solution

    Conforms

    Identity by HPLC

    The retention is same with the reference substance

    Conforms

    Amino acid composition

    gly:0.85~1.10

    pro:0.85~1.10

    leu:0.85~1.10

    cys:1.65~2.20

    asn:0.85~1.10

    gln:0.85~1.10

    ile:0.85~1.10

    tyr:0.85~1.10

    1.02

    1.06

    1.01

    1.88

    0.96

    1.01

    0.99

    1.02

    pH

    3.0~6.0

    5.16

    Specific optical rotation

    c=1,1%hac

    -21.2°

    Purity

    ≥98.0%

    99.12%

    Related substance(by hplc)

    total impurities(%)≤2.0%

    largest single impurity(%)≤1.0%

    0.88%

    0.55%

    Acetate content(by hplc)

    ≤12.0%

    6.7%

    Water

    ≤8%

    5.7%

    Peptide content (n%)

    ≥80.0%

    87.6%

    Bacterial endotoxins

    ≤70iu/mg

    Conforms

    Residual organic solvents

    acetonitrile ≤0.041%(by gc)

    dmf ≤0.088%(by gc)

    meoh ≤0.3% (by gc)

    tfa ≤0.1% (by hplc)

    dcm ≤0.06% (by gc)

    mecn ≤0.041% (by gc)

    Conforms

    Assay

    95%~105%

    99.3%

    Conclusion

    Complies with the standard.

     

    Usage

     

    Function of Oxytocin Acetate

    Oxytocin acetate is a peptide hormone, secreted by the posterior pituitary gland, synthesized by the paraventricular nucleus and supraoptic nucleus of the hypothalamus, composed of 9 amino acids, and transported to the neurohypophysis at a rate of 2 mm to 3 mm per day freed. The cysteine (Cys) residues at positions "1" and "6" form a 6-peptide ring structure in the form of disulfide bonds.

     

    (1) Effect on mammary glands: The breast during lactation continuously secretes milk under the action of prolactin, which is stored in the acinar glands of the breast. Oxytocin can shrink the myoepithelial-like cells around the breast acinar, and promote the breast milk with the lactating function.

    (2) The effect on the uterus: Oxytocin has a strong effect on promoting the contraction of the uterus, but the pregnant uterus is more sensitive. Estrogen can increase the sensitivity of the uterus to oxytocin, while progesterone does the opposite.

     

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