99% up LATANOPROST 130209-82-4

Category:Active Pharmaceutical Ingredients > Prostaglandins
Product Name:99% up LATANOPROST 130209-82-4
CAS No.:130209-82-4
Standard:USP, EP, In-house Standards
Price(USD):Negotiable
Company:Sinoway Industrial Co.Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Xiamen, Fujian

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

  • Monthly Production Capacity: 100kg

    Packaging Information: 1kg/bottle

  • Sample Provided: yes

    Payment Terms: L/L

    Product Information

     

    Product name

    Latanoprost

    Molecular Formula

    C26H40O5

    Molecular Weight

    432.59

    CAS No.

    130209-82-4

    Quality Standard

    99% up, medical grade

    Appearance

    Light yellow oil

     

    COA of Latanoporst

     

    TESTS

    SPECIFICATIONS

    RESULTS

    Description

    Colorless or light yellow oil

    Light yellow oil

    Identification

    A: IR

    B: The retention time of the major peak in the chromatogram of the sample corresponds to that of the standard solution, as obtained in the assay

    Complies

    Water

    NMT 2.0%

    0.05%

    Optical rotation

    +31°~+38°

    +35.2°

    Residue on ignition

    NMT 0.5%

    0.05%

    Related substances (HPLC)

    Isopropyl

    Dipheny lphosphorylpentanoate

    NMT0.1%

    0.06%

    Related compound B

    NMT0.5%

    0.09%

    Related compound A

    NMT3.5%

    N.D

    Any unspecified impurity

    NMT0.1%

    0.06%

    Total other impurities

    NMT0.5%

    0.08%

    Related Compound E

    NMT0.2%

    0.02%

    Residue

    Solvent

    n-Hexane

    NMT0.029%

    Not detected

    Ethanol

    NMT0.5%

    0.15%

    Methanol

    NMT0.3%

    Not detected

    Isopropanol

    NMT0.5%

    Not detected

    Assay

    94.0%~102.0%

    99.77%

    Conclusion: The product complies as per above specification.

     

    Usage

     

    Function of Latanoprost

    Latanoprost is a new type of phenyl substituted prostaglandin F2α, which is a selective F2α receptor agonist. It is an inactive substance that can quickly penetrate into the cornea and can be hydrolyzed into active free acids in the cornea and plasma. It can increase the outflow of aqueous humor through the corneal layer, and the amount of medication is small, but promotes the outflow of aqueous humor. This product can also smooth the trabecular meshwork structure of the glaucoma patients that are usually blocked.

    Latanoprost is a new class of ocular hypotensive drugs developed in recent years and gradually applied to the clinic. Unlike other anti-glaucoma drugs, this product does not change the flow coefficient of the aqueous humor, the production of aqueous humor, and suprascleral venous pressure, but reduces the intraocular pressure by increasing the waterproofing from the uveal scleral passage and outflow.

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