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Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:Gemcitabine hydrochloride
CAS No.:122111-03-9
Standard:ChP, USP, BP, EP, JP, In-house Standards
Price(USD):0.00
Company:Hangzhou Royall Import & Export Co.,Ltd
Grade: Pharmaceutical Grade
Factory Location: hangzhou
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Monthly Production Capacity: 5tons/y
Contract Manufacturing: CRO,CMO
Packaging Information: on discussion
Delivery Lead Time: on discussion
Sample Provided: yes
Payment Terms: L/C T/T or others
Appearance:
White crystalline granular, odorless
Molecular Weight:
299.66
Boiling Point:
482.7 °C at 760 mmHg
Melting Point:
>250°C dec
Flash Point:
245.7 °C
Solubility:
In water, 5.13X10+4 mg/L at 25 deg C (est)
Biological Activity:
Deoxycytidine analog that inhibits DNA synthesis. Metabolized to form gemcitabine triphosphate (dFdCTP) and gemcitabine diphosphate (dFdCDP). dFdCTD inhibits ribonucleotide reductase causing a reduction in cellular nucleotides. dFdCTP is incorporated in DNA resulting in DNA strand termination. Displays antitumor activity in vitro and in vivo .
Usage:
An antineoplastic
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