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Category:Active Pharmaceutical Ingredients > Other Active Pharmaceutical Ingredients
Product Name:Pharmaceutical Grade Osimertinib Mesylate API CAS 1421373-66-1
CAS No.:1421373-66-1
Standard:ChP, USP, BP, EP, JP, In-house Standards, IP, Ph. Int
Price(USD):US$1000~US$2000/Kg
Company:Shandong Loncom Pharmaceutical Co.Ltd.
Grade: Pharmaceutical Grade
Factory Location: China
Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East,Africa
Monthly Production Capacity: 500kg
Contract Manufacturing: CRO,CMO
Packaging Information: 5kg/drum
Delivery Lead Time: 15days
Sample Provided: no
Payment Terms: L/L
Function
Osimertinib is active against exon 19 deletions, exon 21 mutations, and also the exon 20 T790M mutations. It is preferentially selective for mutated EGFR, and therefore toxicity at therapeutic doses is lower than for first- and second-generation agents. Notably, osimertinib is able to cross the blood-brain barrier, making it active against disease in the CNS.
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