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Pivaloyl chloride (2,2-dimethylpropanoyl chloride) is a reactive organic compound classified as an acyl chloride.
Reactivity: The acyl chloride readily undergoes diverse reactions like acylation, amidation, and substitution, enabling introduction of the pivaloyl group (tert-butyl carbonyl) into complex molecules.
Chemical Properties: The bulky tert-butyl group can improve lipophilicity (fat solubility), potentially enhancing drug absorption and bioavailability.
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Pharma Sources Insight January 2025
![3-[(R)-amino(3-amino-4-fluorophenyl)methyl]benzonitrile hydrochloride](https://eimg.pharmasources.com/image/20240227/00LX50XuK1dkOoxnYyGOUw6m88Ms37BdxHetlRUC.jpeg!145)
