(R)-3-(4-Phenoxyphenyl)-1-(Piperidin-3-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine Dihydrochloride Ibrut

Category:Intermediates > Pharmaceutical Intermediates
Product Name:(R)-3-(4-Phenoxyphenyl)-1-(Piperidin-3-Yl)-1H-Pyrazolo[3,4-D]Pyrimidin-4-Amine Dihydrochloride Ibrut
CAS No.:1701403-10-2
Standard:USP, BP, EP, JP, In-house Standards
Price(USD):Negotiable
Company:Sinoway Industrial Co.Ltd.

Basic Info
  • Grade: Pharmaceutical Grade

    Factory Location: Xiamen, Fujian

    Main Sales Markets: North America,Central/South America,Western Europe,Eastern Europe,Australasia,Asia,Middle East

  • Monthly Production Capacity: 1000kg

    Packaging Information: 1kg/bottle

  • Delivery Lead Time: 7 days after payment

    Sample Provided: yes

    Payment Terms: L/L

    Product Information

     

    Product name

    (R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine dihydrochloride ; Ibrutinib intermediate

    CAS No.

    1701403-10-2

    Molecular Formula

    C22H24Cl2N6O

    Molecular Weight

    303.32

    Quality Standard

    99% up by HPLC, GMP

    Appearance

    White powder

     

    Molecular Structure:

    Synonyms:  R)-3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine dihydrochloride

     

    Usage

     

    Function of Ibrutinib

    Ibrutinib is a chemotherapeutic agent, which is mainly used for mantle cell lymphoma, chronic lymphocytic leukemia, small lymphocytic lymphoma and Waldenstrom's macroglobulinemia. It can also be used for diseases such as B-cell malignancies. The drug is a small molecule BTK inhibitor that can inhibit the proliferation and survival of malignant B cells in vivo, as well as cell migration and substrate adhesion in vitro. It cannot be taken with grapefruit juice during the use of the drug, otherwise it will cause the drug Absorb more. At the same time, the drug also has certain side effects, which may cause bleeding in patients, increase the chance of infection, decrease blood cells, interstitial lung disease, arrhythmia, hypertension, and secondary malignant tumors. At the same time, pregnant women are not recommended to take the drug, because the drug may damage the fetus, and the drug may also cause skeletal muscle pain and joint pain.

     

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